CJC-1295 Without DAC

Compound Overview

CJC-1295 Without DAC, also known as Modified GRF 1-29, is a synthetic GHRH analog used to study pituitary GH release through GHRH receptor binding. Because this form does not include the Drug Affinity Complex, it has a shorter research half-life and supports pulsatile GH release patterns that more closely reflect physiological signaling models.

Research Background & Published Literature

Within GH-axis research, CJC-1295 No DAC is commonly evaluated alongside GH secretagogues such as Ipamorelin or GHRP-6 to investigate synergistic GH release mechanisms. Its pulsatile release profile makes it useful for experiments focused on natural GH secretion patterns.

Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:

• Teichman et al. (2006) — J Clin Endocrinol Metab
• Memdouh et al. (2021) — Drug Test Anal
• Coppieters et al. (2022) — J Pharm Biomed Anal

Storage, Handling & Stability Guidelines

Store lyophilized CJC-1295 Without DAC at -20°C. After reconstitution, keep research material refrigerated at 2–8°C and use within 14 days.

• Keep ambient-temperature exposure brief during handling to help preserve compound integrity.
• Reseal vials promptly after each withdrawal to reduce moisture exposure.
• Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
• For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.

Lab Verification

Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.