Sermorelin Acetate
Sermorelin Acetate from the Nexus Growth Hormone Secretagogues catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
Sermorelin is a synthetic 29-amino acid peptide representing the bioactive N-terminal fragment of native GHRH (1-44). It binds the GHRH receptor on anterior pituitary somatotrophs, stimulating endogenous GH synthesis and secretion through a physiological pulsatile pattern.
No sequence is listed in the current catalog record for this product.
- CAS
- 86168-78-7
- MW
- 3357.93 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C149H246N44O42S
- Purity
- 99.42%
- Form
- Lyophilized powder
- Class
- Growth Hormone-Releasing Hormone (GHRH) Fragment
The dossier.
Compound Overview
Sermorelin is a synthetic 29-amino acid peptide corresponding to the bioactive N-terminal fragment of native GHRH (1-44). In controlled research contexts, it is studied for binding at the GHRH receptor on anterior pituitary somatotrophs and for signaling associated with endogenous GH synthesis and secretion through a physiological pulsatile pattern.
Research Background & Published Literature
Historical clinical literature includes the branded product Geref as a diagnostic agent for evaluating pituitary GH function; Nexus supplies Sermorelin Acetate strictly as research-grade material for in-vitro laboratory use only, and it is not approved for any human application. Sermorelin remains a benchmark compound in GHRH receptor research, with published pharmacology discussed in Endocrine Reviews and Journal of Clinical Endocrinology & Metabolism.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep ambient-temperature handling time brief to help preserve compound integrity.
- Reseal vials promptly after each withdrawal to reduce moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 86168-78-7
- Molecular Weight
- 3357.93 g/mol
- Molecular Formula
- C₁₄₉H₂₄₆N₄₄O₄₂S
- Class
- Growth Hormone-Releasing Hormone (GHRH) Fragment
Research context.
The branded clinical product Geref was historically used as a diagnostic agent for evaluating pituitary GH function in clinical practice; This material is supplied strictly for in-vitro research use only and is not approved for any human application. Extensive published pharmacology in Endocrine Reviews and Journal of Clinical Endocrinology & Metabolism. A benchmark compound for GHRH receptor research.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.42%
- Retention time
- 13.50 min
- Observed mass
- 3358.17 Da
- Batch
- APX-2026-0317-S
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0317-S- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
29-amino acid peptide (GHRH 1-29), the bioactive N-terminal fragment of GHRH
Technical specifications.
- Product Name: Sermorelin Acetate
- Classification: Growth Hormone-Releasing Hormone (GHRH) Fragment
- Structural Description: 29-amino acid peptide (GHRH 1-29), the bioactive N-terminal fragment of GHRH
- CAS Number: 86168-78-7
- Molecular Weight: 3357.93 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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Research notes.
Sermorelin Acetate research FAQ.
What is Sermorelin Acetate used for in research?
Sermorelin Acetate is supplied for controlled in-vitro research workflows in the Growth Hormone Secretagogues category. It is not labeled for human or veterinary use.
Does Sermorelin Acetate have a finalized analytical record?
Sermorelin Acetate has a finalized Nexus Lab Verified record that reports 99.42% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which Sermorelin Acetate variants are published?
Published Nexus variants include 2mg, 5mg, 10mg, 15mg.
Does Sermorelin Acetate include a COA?
Yes. The current Nexus record links Sermorelin Acetate to finalized batch APX-2026-0317-S.