Sermorelin Acetate
Sermorelin Acetate from the Nexus Growth Hormone Secretagogues catalog, supplied for controlled in-vitro research workflows.
In stock: 2mg is in stock.
For in-vitro research use only. Not for human consumption.
Sermorelin is a synthetic 29-amino acid peptide representing the bioactive N-terminal fragment of native GHRH (1-44). It binds the GHRH receptor on anterior pituitary somatotrophs, stimulating endogenous GH synthesis and secretion through a physiological pulsatile pattern.
No sequence is listed in the current catalog record for this product.
- CAS
- 86168-78-7
- MW
- 3357.93 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C149H246N44O42S
- Purity
- 99.42%
- Form
- Lyophilized powder
- Class
- Growth Hormone-Releasing Hormone (GHRH) Fragment
This lyophilized research material is commonly paired with bacteriostatic water for reconstitution workflows.
Add bacteriostatic waterThe dossier.
Compound Overview
Sermorelin is a synthetic 29-amino acid peptide corresponding to the bioactive N-terminal fragment of native GHRH (1-44). In controlled research contexts, it is studied for binding at the GHRH receptor on anterior pituitary somatotrophs and for signaling associated with endogenous GH synthesis and secretion through a physiological pulsatile pattern.
Research Background & Published Literature
Historical clinical literature includes the branded product Geref as a diagnostic agent for evaluating pituitary GH function; Nexus supplies Sermorelin Acetate strictly as research-grade material for in-vitro laboratory use only, and it is not approved for any human application. Sermorelin remains a benchmark compound in GHRH receptor research, with published pharmacology discussed in Endocrine Reviews and Journal of Clinical Endocrinology & Metabolism.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
Storage, Handling & Stability Guidelines
Store lyophilized Sermorelin Acetate at -20°C for long-term stability. After reconstitution with sterile diluent, keep research material refrigerated at 2–8°C and reduce freeze-thaw exposure by aliquoting working volumes according to your laboratory's standard operating procedures.
- Keep ambient-temperature handling time brief to help preserve compound integrity.
- Reseal vials promptly after each withdrawal to reduce moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Lab Verification
Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Compounds are supplied as lyophilized research material — follow the storage and reconstitution guidance on the product page and its Certificate of Analysis.
Compound details.
- CAS Number
- 86168-78-7
- Molecular Weight
- 3357.93 g/mol
- Molecular Formula
- C₁₄₉H₂₄₆N₄₄O₄₂S
- Class
- Growth Hormone-Releasing Hormone (GHRH) Fragment
- Purity
- ≥99% purity
- Physical Form
- Lyophilized powder
- Storage
- Store at -20°C (long term). Refrigerate after reconstitution.
Research context.
The branded clinical product Geref was historically used as a diagnostic agent for evaluating pituitary GH function in clinical practice; This material is supplied strictly for in-vitro research use only and is not approved for any human application. Extensive published pharmacology in Endocrine Reviews and Journal of Clinical Endocrinology & Metabolism. A benchmark compound for GHRH receptor research.
Verification standard.
Independently verified Nexus Laboratory batches ship with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin context where applicable — verified by independent third-party laboratories and publicly archived; lots awaiting final documentation are labeled certificate pending instead of showing assay values. Review Nexus lab verification.
HPLC trace.
- HPLC purity
- 99.42%
- Retention time
- 13.5 min
- Batch
- NEX-SERMORELIN-ACETATE-2026-0079
The full reverse-phase HPLC chromatogram, peak integration table, and mass-spectrometry identity confirmation for this batch are published on the certificate of analysis.
View certificate of analysis - batch NEX-SERMORELIN-ACETATE-2026-0079- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
29-amino acid peptide (GHRH 1-29), the bioactive N-terminal fragment of GHRH
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: Sermorelin Acetate
- Classification: Growth Hormone-Releasing Hormone (GHRH) Fragment
- Structural Description: 29-amino acid peptide (GHRH 1-29), the bioactive N-terminal fragment of GHRH
- CAS Number: 86168-78-7
- Molecular Weight: 3357.93 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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Research notes.
Sermorelin Acetate research FAQ.
What is Sermorelin Acetate used for in research?
Sermorelin Acetate is supplied for controlled in-vitro research workflows in the Growth Hormone Secretagogues category. It is not labeled for human or veterinary use.
Is Sermorelin Acetate HPLC verified?
Sermorelin Acetate has a finalized Nexus Lab Verified record with 99.42% HPLC purity context in the current COA data.
Which Sermorelin Acetate sizes are available?
Current Nexus variants include 2mg, 5mg, 10mg, 15mg.
Does Sermorelin Acetate include a COA?
Yes. The current Nexus record links Sermorelin Acetate to verified batch NEX-SERMORELIN-ACETATE-2026-0079.