Hexarelin Acetate

Compound Overview

Hexarelin is a potent synthetic hexapeptide GH secretagogue studied for activation of the ghrelin receptor (GHSR-1a) and cardiac receptors (CD36). Within controlled research models, it is characterized as a high-potency GHRP by GH-release assay response. Its distinctive cardiac receptor activity separates it from other GHRPs and makes it useful for investigating cardiovascular-endocrine crosstalk in laboratory systems.

Research Background & Published Literature

Research published in Journal of Endocrinological Investigation and Growth Hormone & IGF Research has examined Hexarelin's paired GH-releasing activity and cardiac-receptor signaling profile. Studies have also evaluated its interaction with CD36 receptors in cardiac tissue models.

Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:

• Bodart et al. (2002) — Circ Res
• Mosa et al. (2017) — Endocrinology
• Cheng et al. (2019) — Peptides

Storage, Handling & Stability Guidelines

Store lyophilized Hexarelin Acetate at -20°C for long-term stability. After reconstitution with sterile diluent, refrigerate at 2–8°C and reduce freeze-thaw exposure by aliquoting working volumes according to your laboratory's standard operating procedures.

• Keep ambient-temperature handling time brief to help preserve compound integrity.
• Reseal vials promptly after each withdrawal to reduce moisture exposure.
• Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
• For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.

Lab Verification

Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.