Selank

Compound Overview

Selank is a synthetic heptapeptide built from the tuftsin sequence (Thr-Lys-Pro-Arg) with a Pro-Gly-Pro extension. Controlled laboratory research examines its modulation of BDNF, serotonin (5-HT), dopamine, and enkephalin signaling, along with anxiolytic, nootropic, and immunomodulatory properties.

Research Background & Published Literature

Selank was developed at the Institute of Molecular Genetics, Russian Academy of Sciences, and has been published in Bulletin of Experimental Biology and Medicine. Preclinical literature has studied cognitive enhancement, anxiolytic effects, and immune modulation in controlled experimental models.

Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:

• Czabak-Garbacz et al. (2006) — Pharmacol Rep
• Filatova et al. (2017) — Front Pharmacol
• Kolik et al. (2019) — Bull Exp Biol Med

Storage, Handling & Stability Guidelines

For long-term stability, keep lyophilized Selank material stored at -20°C. After reconstitution with sterile diluent, refrigerate at 2–8°C and reduce freeze-thaw exposure by aliquoting working volumes according to validated laboratory SOPs.

• Keep ambient-temperature handling time as short as practical to support compound integrity.
• Reseal vials promptly after each withdrawal to limit moisture exposure.
• Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
• For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.

Lab Verification

Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.