cagrilintide
cagrilintide from the Nexus GLP-1 & Metabolic catalog, supplied for controlled in-vitro research workflows.
In stock: 5mg is in stock.
For in-vitro research use only. Not for human consumption.
Cagrilintide is an acylated, long-acting analog of human amylin. It binds amylin receptors (AMY1, AMY2, AMY3) and calcitonin receptors, modulating appetite, gastric emptying, and postprandial glucose signaling. Its fatty acid acylation extends research half-life through albumin binding.
No sequence is listed in the current catalog record for this product.
- CAS
- 1415456-99-3
- MW
- 4409.07 Da
- Sequence
- Not listed
- Half-life
- Discussed in research notes
- Formula
- C194H312N54O59S2
- Purity
- 99.70%
- Form
- Lyophilized powder
- Class
- Amylin Receptor Agonist
This lyophilized research material is commonly paired with bacteriostatic water for reconstitution workflows.
Browse bacteriostatic waterThe dossier.
Compound Overview
Cagrilintide is an acylated, long-acting analog of human amylin. In laboratory research models, it binds amylin receptors (AMY1, AMY2, AMY3) and calcitonin receptors, where it modulates appetite, gastric emptying, and postprandial glucose signaling. Its fatty acid acylation supports an extended research half-life through albumin binding.
Research Background & Published Literature
Cagrilintide has been evaluated within the CagriSema combination research approach alongside semaglutide. Phase 2 and 3 clinical data have examined amylin-based signaling as a pathway that can be studied in parallel with incretin-based approaches.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
Storage, Handling & Stability Guidelines
Store lyophilized Cagrilintide at -20°C. After reconstitution, keep material at 2–8°C and use within 14 days.
- Keep ambient-temperature handling time as short as practical to support compound integrity.
- Reseal vials promptly after each withdrawal to limit moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Lab Verification
Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Compounds are supplied as lyophilized research material — follow the storage and reconstitution guidance on the product page and its Certificate of Analysis.
Compound details.
- CAS Number
- 1415456-99-3
- Molecular Weight
- 4409.07 Da
- Molecular Formula
- C₁₉₄H₃₁₂N₅₄O₅₉S₂
- Class
- Amylin Receptor Agonist
- Purity
- ≥99% purity
- Physical Form
- Lyophilized powder
- Storage
- Store at -20°C (long term). Refrigerate after reconstitution.
Research context.
Cagrilintide has been studied as part of the CagriSema combination approach (with semaglutide) in metabolic research. Phase 2 and 3 clinical data have explored amylin-based signaling as a complementary pathway to incretin-based approaches.
Verification standard.
Independently verified Nexus Laboratory batches ship with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin context where applicable — verified by independent third-party laboratories and publicly archived; lots awaiting final documentation are labeled certificate pending instead of showing assay values. Review Nexus lab verification.
HPLC trace.
- HPLC purity
- 99.70%
- Retention time
- 16 min
- Batch
- NEX-CAGRILINTIDE-2026-0019
The full reverse-phase HPLC chromatogram, peak integration table, and mass-spectrometry identity confirmation for this batch are published on the certificate of analysis.
View certificate of analysis - batch NEX-CAGRILINTIDE-2026-0019- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
Long-acting amylin analog, acylated synthetic peptide
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: Cagrilintide
- Classification: Amylin Receptor Agonist
- Structural Description: Long-acting amylin analog, acylated synthetic peptide
- CAS Number: 1415456-99-3
- Molecular Weight: 4409.07 Da
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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cagrilintide research FAQ.
What is cagrilintide used for in research?
cagrilintide is supplied for controlled in-vitro research workflows in the GLP-1 & Metabolic category. It is not labeled for human or veterinary use.
Is cagrilintide HPLC verified?
cagrilintide has a finalized Nexus Lab Verified record with 99.70% HPLC purity context in the current COA data.
Which cagrilintide sizes are available?
Current Nexus variants include 5mg, 10mg, 20mg.
Does cagrilintide include a COA?
Yes. The current Nexus record links cagrilintide to verified batch NEX-CAGRILINTIDE-2026-0019.