Semaglutide
Semaglutide from the Nexus GLP-1 & Metabolic catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
Semaglutide is a modified GLP-1 analog engineered with an albumin-binding fatty acid side chain that extends its half-life in research models. It binds and activates the GLP-1 receptor, which plays a central role in glucose homeostasis and appetite regulation pathways.
No sequence is listed in the current catalog record for this product.
- CAS
- 910463-68-2
- MW
- 4113.58 g/mol
- Sequence
- Not listed
- Half-life
- Discussed in research notes
- Formula
- C187H291N45O59
- Purity
- 99.52%
- Form
- Lyophilized powder
- Class
- GLP-1 Receptor Agonist
The dossier.
Compound Overview
Semaglutide is a modified GLP-1 analog designed with an albumin-binding fatty acid side chain that extends its half-life in research models. In controlled laboratory systems, it binds and activates the GLP-1 receptor, a receptor system studied for its role in glucose homeostasis and appetite regulation pathways.
Research Background & Published Literature
Semaglutide is among the most widely studied peptides in contemporary metabolic research. It has appeared across the STEP, SUSTAIN, and PIONEER clinical trial programs, with published literature covering glycemic control, cardiovascular outcomes, and metabolic signaling. Within GLP-1 receptor research, it remains a benchmark compound for comparator studies in laboratories worldwide.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep time at ambient temperature as short as practical during handling to support compound integrity.
- Reseal vials promptly after each withdrawal to limit moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 910463-68-2
- Molecular Weight
- 4113.58 g/mol
- Molecular Formula
- C₁₈₇H₂₉₁N₄₅O₅₉
- Class
- GLP-1 Receptor Agonist
Research context.
One of the most extensively studied peptides in modern metabolic research, Semaglutide has been the subject of the STEP, SUSTAIN, and PIONEER clinical trial programs. Published data spans applications in glycemic control, cardiovascular outcomes, and metabolic signaling. It remains a benchmark compound for GLP-1 receptor studies in laboratories worldwide.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.52%
- Retention time
- 16.50 min
- Observed mass
- 4113.46 Da
- Batch
- APX-2026-0305-S
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0305-S- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
31-amino acid GLP-1 analog with a C-18 fatty diacid chain
Technical specifications.
- Product Name: Semaglutide
- Classification: GLP-1 Receptor Agonist
- Structural Description: 31-amino acid GLP-1 analog with a C-18 fatty diacid chain
- CAS Number: 910463-68-2
- Molecular Weight: 4113.58 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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Semaglutide research FAQ.
What is Semaglutide used for in research?
Semaglutide is supplied for controlled in-vitro research workflows in the GLP-1 & Metabolic category. It is not labeled for human or veterinary use.
Does Semaglutide have a finalized analytical record?
Semaglutide has a finalized Nexus Lab Verified record that reports 99.52% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which Semaglutide variants are published?
Published Nexus variants include 2mg, 5mg, 10mg, 15mg, 20mg, 30mg.
Does Semaglutide include a COA?
Yes. The current Nexus record links Semaglutide to finalized batch APX-2026-0305-S.