cagrilintide 5mg+Semaglutide 5mg
cagrilintide 5mg+Semaglutide 5mg from the Nexus GLP-1 & Metabolic catalog, supplied for controlled in-vitro research workflows.
In stock: 10mg is in stock.
For in-vitro research use only. Not for human consumption.
CagriSema combines Cagrilintide (an amylin receptor agonist) with Semaglutide (a GLP-1 receptor agonist) to enable research into dual-pathway metabolic signaling. This combination targets amylin receptors and GLP-1 receptors simultaneously, two complementary pathways involved in appetite regulation and metabolic homeostasis.
No sequence is listed in the current catalog record for this product.
- CAS
- N/A
- MW
- Cagrilintide: 4409.07 g/mol + Semaglutide: 4113.58 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- Not listed
- Purity
- ≥99% purity
- Form
- Lyophilized powder
- Class
- Dual Amylin/GLP-1 Combination
This lyophilized research material is commonly paired with bacteriostatic water for reconstitution workflows.
Pair with bacteriostatic waterThe dossier.
Compound Overview
CagriSema pairs Cagrilintide, an amylin receptor agonist, with Semaglutide, a GLP-1 receptor agonist, so researchers can examine dual-pathway metabolic signaling in controlled laboratory models. The blend is designed for simultaneous study of amylin receptors and GLP-1 receptors, two complementary signaling systems associated with appetite regulation and metabolic homeostasis research.
Research Background & Published Literature
The CagriSema combination has been evaluated in Phase 3 clinical trials focused on dual amylin/GLP-1 pathway activation. This research model provides a way to study how two distinct hormonal signaling systems may interact during metabolic regulation experiments.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
Storage, Handling & Stability Guidelines
Store the lyophilized blend at -20°C. After reconstitution, keep research material at 2–8°C and use within 14 days.
- Keep ambient-temperature exposure as brief as practical during handling to support compound integrity.
- Reseal vials promptly after each withdrawal to limit moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Lab Verification
Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Compounds are supplied as lyophilized research material — follow the storage and reconstitution guidance on the product page and its Certificate of Analysis.
Compound details.
- Molecular Weight
- Cagrilintide: 4409.07 g/mol + Semaglutide: 4113.58 g/mol
- Class
- Dual Amylin/GLP-1 Combination
- Purity
- ≥99% purity
- Physical Form
- Lyophilized powder
- Storage
- Store at -20°C (long term). Refrigerate after reconstitution.
Research context.
The CagriSema combination has been evaluated in Phase 3 clinical trials studying dual amylin/GLP-1 pathway activation. This represents a novel approach to studying how two distinct hormonal signaling systems interact in metabolic regulation.
Verification standard.
Independently verified Nexus Laboratory batches ship with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin context where applicable — verified by independent third-party laboratories and publicly archived; lots awaiting final documentation are labeled certificate pending instead of showing assay values. Review Nexus lab verification.
HPLC trace.
- HPLC purity
- ≥99% purity
- Retention time
- See COA
- Batch
- NEX-CAGRILINTIDE-5MG-PLUS-SEMAGL-2026-0020
The full reverse-phase HPLC chromatogram, peak integration table, and mass-spectrometry identity confirmation for this batch are published on the certificate of analysis.
View certificate of analysis - batch NEX-CAGRILINTIDE-5MG-PLUS-SEMAGL-2026-0020- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
Fixed-dose combination of Cagrilintide (amylin analog) and Semaglutide (GLP-1 agonist)
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: Cagrisema (2.5mg+2.5mg)
- Classification: Dual Amylin/GLP-1 Combination
- Structural Description: Fixed-dose combination of Cagrilintide (amylin analog) and Semaglutide (GLP-1 agonist)
- Molecular Weight: Cagrilintide: 4409.07 g/mol + Semaglutide: 4113.58 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
Related research compounds
Comparable catalog records with live availability and certificate status.
- GLP-1 & MetabolicVerified batchSemaglutidePriceFrom $14.99Formats6 sizes
Compare size options, price, and certificate status before opening the product record.
CAS 910463-68-2View product - GLP-1 & MetabolicVerified batchTirzepatidePriceFrom $28.99Formats10 sizes
Compare size options, price, and certificate status before opening the product record.
CAS 2023788-19-2View product - GLP-1 & MetabolicVerified batchRetatrutidePriceFrom $45.99Formats8 sizes
Compare size options, price, and certificate status before opening the product record.
CAS 2381089-83-2View product - GLP-1 & MetabolicVerified batchLiraglutidePriceFrom $113.99Formats3 sizes
Compare size options, price, and certificate status before opening the product record.
CAS 204656-20-2View product - GLP-1 & MetabolicVerified batchMazdutidePriceFrom $94.99Formats2 sizes
Compare size options, price, and certificate status before opening the product record.
CAS 2259884-03-0View product
Research notes.
cagrilintide 5mg+Semaglutide 5mg research FAQ.
What is cagrilintide 5mg+Semaglutide 5mg used for in research?
cagrilintide 5mg+Semaglutide 5mg is supplied for controlled in-vitro research workflows in the GLP-1 & Metabolic category. It is not labeled for human or veterinary use.
Is cagrilintide 5mg+Semaglutide 5mg HPLC verified?
cagrilintide 5mg+Semaglutide 5mg has a finalized Nexus Lab Verified record with batch-specific HPLC purity context in the current COA data.
Which cagrilintide 5mg+Semaglutide 5mg sizes are available?
Current Nexus variants include 10mg.
Does cagrilintide 5mg+Semaglutide 5mg include a COA?
Yes. The current Nexus record links cagrilintide 5mg+Semaglutide 5mg to verified batch NEX-CAGRILINTIDE-5MG-PLUS-SEMAGL-2026-0020.