PEG MGF
PEG MGF from the Nexus Growth Hormone Secretagogues catalog, supplied for controlled in-vitro research workflows.
In stock: 2mg is in stock.
For in-vitro research use only. Not for human consumption.
PEG-MGF is a PEGylated form of Mechano Growth Factor, a splice variant of IGF-1 (specifically the Ec isoform). MGF is produced in response to mechanical stimulation of muscle tissue. The PEGylation extends the research half-life by reducing enzymatic degradation. Research examines its role in satellite cell activation and muscle tissue repair signaling.
PEG MGF definition
MGF is the unpegylated mechano growth factor peptide SKU. It is distinct from PEG-MGF and should not inherit PEG-MGF molecular-weight data. MGF is classified as a igf-1ec / mechano growth factor peptide. Supplied for controlled in-vitro research workflows.
No sequence is listed in the current catalog record for this product.
- CAS
- 108174-48-7
- MW
- ~24,000-26,000 g/mol (PEGylated peptide)
- Sequence
- Not listed
- Half-life
- Discussed in research notes
- Formula
- C121H200N42O39
- Purity
- 99.83%
- Form
- Lyophilized powder
- Class
- PEGylated Growth Factor Variant
This lyophilized research material is commonly paired with bacteriostatic water for reconstitution workflows.
Browse bacteriostatic waterThe dossier.
Compound Overview
PEG-MGF is the PEGylated form of Mechano Growth Factor, an IGF-1 splice variant specifically associated with the Ec isoform. MGF is produced in response to mechanical stimulation of muscle tissue. PEGylation is used in research contexts to extend the research half-life by reducing enzymatic degradation. Laboratory studies examine PEG-MGF in relation to satellite cell activation and muscle tissue repair signaling.
Research Background & Published Literature
MGF signaling has been discussed in publications such as Journal of Applied Physiology and FASEB Journal, with research focused on how mechanical loading activates IGF-1 splice variants and how those variants relate to muscle hypertrophy and regeneration pathways in controlled laboratory models.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
- Qin et al. (2012) — Mol Cell Biochem
- Fornaro et al. (2014) — Am J Physiol Endocrinol Metab
- Tang et al. (2017) — Mol Brain
Storage, Handling & Stability Guidelines
Store lyophilized PEG-MGF at -20°C for long-term stability. After reconstitution with sterile diluent, keep research material refrigerated at 2–8°C and minimize freeze-thaw cycles by aliquoting working volumes according to your standard operating procedures.
- Keep ambient-temperature exposure brief during handling to help preserve compound integrity.
- Reseal vials promptly after each withdrawal to reduce moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Lab Verification
Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Compounds are supplied as lyophilized research material — follow the storage and reconstitution guidance on the product page and its Certificate of Analysis.
Compound details.
- Molecular Weight
- 2867.15 g/mol
- Molecular Formula
- C121H200N42O39
- Class
- IGF-1Ec / mechano growth factor peptide
- Physical Form
- Lyophilized powder
- Storage
- Store lyophilized material at -20C, desiccated and protected from light. After reconstitution, aliquot and avoid repeated freeze-thaw cycles.
Research context.
MGF is studied in preclinical research models examining mechanisms relevant to the ghrh analogs, gh secretagogues, and growth-factor research compounds. Independently verified Nexus Laboratory batches are documented through third-party HPLC purity verification, mass spectrometry identity confirmation, and endotoxin context where applicable; lots awaiting final documentation are labeled certificate pending. Compounds are supplied strictly for in-vitro and analytical research use.
Verification standard.
Independently verified Nexus Laboratory batches ship with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin context where applicable — verified by independent third-party laboratories and publicly archived; lots awaiting final documentation are labeled certificate pending instead of showing assay values. Review Nexus lab verification.
HPLC trace.
- HPLC purity
- 99.83%
- Retention time
- 14.5 min
- Batch
- NEX-PEG-MGF-2026-0067
The full reverse-phase HPLC chromatogram, peak integration table, and mass-spectrometry identity confirmation for this batch are published on the certificate of analysis.
View certificate of analysis - batch NEX-PEG-MGF-2026-0067- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
PEGylated Mechano Growth Factor — PEGylated form of the IGF-1Ec splice variant
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: PEG-MGF 2mg
- Classification: PEGylated Growth Factor Variant
- Structural Description: PEGylated Mechano Growth Factor — PEGylated form of the IGF-1Ec splice variant
- Molecular Weight: ~24,000-26,000 g/mol (PEGylated peptide)
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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PEG MGF research FAQ.
What is PEG MGF used for in research?
PEG MGF is supplied for controlled in-vitro research workflows in the Growth Hormone Secretagogues category. It is not labeled for human or veterinary use.
Is PEG MGF HPLC verified?
PEG MGF has a finalized Nexus Lab Verified record with 99.83% HPLC purity context in the current COA data.
Which PEG MGF sizes are available?
Current Nexus variants include 2mg.
Does PEG MGF include a COA?
Yes. The current Nexus record links PEG MGF to verified batch NEX-PEG-MGF-2026-0067.