PEG MGF
PEG MGF from the Nexus Growth Hormone Secretagogues catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
PEG-MGF is a PEGylated form of Mechano Growth Factor, a splice variant of IGF-1 (specifically the Ec isoform). MGF is produced in response to mechanical stimulation of muscle tissue. The PEGylation extends the research half-life by reducing enzymatic degradation. Research examines its role in satellite cell activation and muscle tissue repair signaling.
PEG MGF definition
MGF is the unpegylated mechano growth factor peptide SKU. It is distinct from PEG-MGF and should not inherit PEG-MGF molecular-weight data. MGF is classified as a igf-1ec / mechano growth factor peptide. Supplied for controlled in-vitro research workflows.
No sequence is listed in the current catalog record for this product.
- CAS
- 108174-48-7
- MW
- ~24,000-26,000 g/mol (PEGylated peptide)
- Sequence
- Not listed
- Half-life
- Discussed in research notes
- Formula
- C121H200N42O39
- Purity
- 99.83%
- Form
- Lyophilized powder
- Class
- PEGylated Growth Factor Variant
The dossier.
Compound Overview
PEG-MGF is the PEGylated form of Mechano Growth Factor, an IGF-1 splice variant specifically associated with the Ec isoform. MGF is produced in response to mechanical stimulation of muscle tissue. PEGylation is used in research contexts to extend the research half-life by reducing enzymatic degradation. Laboratory studies examine PEG-MGF in relation to satellite cell activation and muscle tissue repair signaling.
Research Background & Published Literature
MGF signaling has been discussed in publications such as Journal of Applied Physiology and FASEB Journal, with research focused on how mechanical loading activates IGF-1 splice variants and how those variants relate to muscle hypertrophy and regeneration pathways in controlled laboratory models.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
- Qin et al. (2012) — Mol Cell Biochem
- Fornaro et al. (2014) — Am J Physiol Endocrinol Metab
- Tang et al. (2017) — Mol Brain
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep ambient-temperature exposure brief during handling to help preserve compound integrity.
- Reseal vials promptly after each withdrawal to reduce moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- Molecular Weight
- 2867.15 g/mol
- Molecular Formula
- C121H200N42O39
- Class
- IGF-1Ec / mechano growth factor peptide
Research context.
MGF vendor records typically define a short half-life unpegylated peptide, while PEG-MGF has a polymer modification and variable mass.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.83%
- Retention time
- 14.50 min
- Observed mass
- 2867.36 Da
- Batch
- APX-2026-0403-P
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0403-P- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
PEGylated Mechano Growth Factor — PEGylated form of the IGF-1Ec splice variant
Technical specifications.
- Product Name: PEG-MGF 2mg
- Classification: PEGylated Growth Factor Variant
- Structural Description: PEGylated Mechano Growth Factor — PEGylated form of the IGF-1Ec splice variant
- Molecular Weight: ~24,000-26,000 g/mol (PEGylated peptide)
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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PEG MGF research FAQ.
What is PEG MGF used for in research?
PEG MGF is supplied for controlled in-vitro research workflows in the Growth Hormone Secretagogues category. It is not labeled for human or veterinary use.
Does PEG MGF have a finalized analytical record?
PEG MGF has a finalized Nexus Lab Verified record that reports 99.83% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which PEG MGF variants are published?
Published Nexus variants include 2mg.
Does PEG MGF include a COA?
Yes. The current Nexus record links PEG MGF to finalized batch APX-2026-0403-P.