PTD-DBM

Compound Overview

Research Use Only. Not for Human Consumption.

PTD-DBM is supplied by Nexus as a 5mg lyophilized research peptide in the Cognitive & Nootropic category. The supplied research record classifies PTD-DBM as a cell-penetrating Wnt pathway research peptide and describes it as a protein transduction domain fused to a Dishevelled-binding motif.

The chemistry record identifies the sequence as RRRRRRRRGGGGRKTGHQICKFRKC, with an expanded amino-acid display of Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Gly-Gly-Gly-Arg-Lys-Thr-Gly-His-Gln-Ile-Cys-Lys-Phe-Arg-Lys-Cys. The same source lists a molecular weight of 3082.6 g/mol and molecular formula of C₁₂₄H₂₂₅N₆₁O₂₈S₂.

This product page is intentionally constrained by the provided product and research data. The source data does not provide a confirmed CAS number, purity value, lot number, batch-specific COA values, HPLC retention-time values, chromatogram data, or mass-spectrum output. Those fields are therefore not inferred from adjacent materials or external assumptions.

• Product: PTD-DBM
• Available Research Size: 5mg
• SKU: PTD5
• Catalog Category: Cognitive & Nootropic
• Classification: Cell-penetrating Wnt pathway research peptide
• Structural Description: Protein transduction domain fused to a Dishevelled-binding motif
• Physical Form: Lyophilized powder
• Use: For in-vitro research use only. Not for human consumption.

Research Background & Published Literature

The supplied research summary describes PTD-DBM as a synthetic cell-penetrating peptide used to study Wnt/beta-catenin pathway modulation through CXXC5-Dvl interaction models. That statement supports a narrow research positioning: PTD-DBM is a pathway-focused peptide reagent for controlled in-vitro study, not a finished clinical, diagnostic, veterinary, or therapeutic product.

The research record states that the PubChem record provides the strongest public structure anchor currently available for this Nexus-only SKU. For that reason, this page treats the supplied sequence, molecular weight, formula, and structural description as the primary identity fields. The available background does not include peer-reviewed citation metadata, experimental model details, assay conditions, quantitative activity values, stability-study data, or protocol recommendations.

The provided source list includes the following references:

These sources are listed because they appear in the supplied research data. They should not be interpreted as lot-specific analytical documentation, proof of purity, or confirmation of any human-use, veterinary-use, diagnostic, therapeutic, or disease-related application.

Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:

• Lee et al. (2015) — J Exp Med
• Ryu et al. (2023) — Cells
• Lee et al. (2023) — Adv Healthc Mater

Storage, Handling & Stability Guidelines

The supplied storage guidance is to store lyophilized PTD-DBM at -20°C, desiccated, and protected from light. After reconstitution, the source record advises aliquoting the material and avoiding repeated freeze-thaw cycles. These are the only storage and stability instructions included in the provided research data.

• Store sealed lyophilized material at -20°C.
• Maintain desiccated storage conditions to limit moisture exposure.
• Protect the vial from light during storage and handling.
• After reconstitution, aliquot according to validated laboratory SOPs.
• Avoid repeated freeze-thaw cycles after reconstitution.
• Maintain traceability between SKU PTD5, the received vial, internal inventory records, and any available analytical documentation.

The supplied data does not provide a validated reconstitution solvent, working concentration, post-reconstitution expiration interval, stability-study result, temperature-excursion tolerance, or packaging validation. Those values should not be inferred from unrelated peptide listings or informal protocol summaries.

Lab Verification

Nexus maintains research-compound verification information through the Lab Verified archive. For PTD-DBM, the supplied source data does not include exact COA values, batch numbers, purity percentages, HPLC retention-time values, chromatogram data, or mass-spectrum values, so this description does not present a lot-specific COA panel.

In general terms, peptide identity and quality review may include HPLC purity assessment and Mass Spectrometry identity confirmation where current lot documentation is available. For PTD-DBM specifically, HPLC/MS review should be reconciled against the provided sequence, listed molecular weight, listed molecular formula, product name, SKU, and received vial label.

Before initiating an in-vitro workflow, review the current documentation available through /lab-verified and maintain internal traceability between the vial, catalog variant, and any available verification record.