PTD-DBM

Compound Overview

Research Use Only. Not for Human Consumption.

PTD-DBM is supplied by Nexus as a 5mg lyophilized research peptide in the Cognitive & Nootropic category. The supplied research record classifies PTD-DBM as a cell-penetrating Wnt pathway research peptide and describes it as a protein transduction domain fused to a Dishevelled-binding motif.

The chemistry record identifies the sequence as RRRRRRRRGGGGRKTGHQICKFRKC, with an expanded amino-acid display of Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Gly-Gly-Gly-Arg-Lys-Thr-Gly-His-Gln-Ile-Cys-Lys-Phe-Arg-Lys-Cys. The same source lists a molecular weight of 3082.6 g/mol and molecular formula of C₁₂₄H₂₂₅N₆₁O₂₈S₂.

• Product: PTD-DBM
• Available Research Size: 5mg
• SKU: PTD5
• Catalog Category: Cognitive & Nootropic
• Classification: Cell-penetrating Wnt pathway research peptide
• Structural Description: Protein transduction domain fused to a Dishevelled-binding motif
• Physical Form: Lyophilized powder
• Use: For in-vitro research use only. Not for human consumption.

Research Background & Published Literature

The supplied research summary describes PTD-DBM as a synthetic cell-penetrating peptide used to study Wnt/beta-catenin pathway modulation through CXXC5-Dvl interaction models. That statement supports a narrow research positioning: PTD-DBM is a pathway-focused peptide reagent for controlled in-vitro study, not a finished clinical, diagnostic, veterinary, or therapeutic product.

The research record states that the PubChem record provides the strongest public structure anchor currently available for this Nexus-only SKU. For that reason, this page treats the supplied sequence, molecular weight, formula, and structural description as the primary identity fields. The available background does not include peer-reviewed citation metadata, experimental model details, assay conditions, quantitative activity values, stability-study data, or protocol recommendations.

The provided source list includes the following references:

These sources are listed because they appear in the supplied research data. They should not be interpreted as lot-specific analytical documentation, proof of purity, or confirmation of any human-use, veterinary-use, diagnostic, therapeutic, or disease-related application.

Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:

• Lee et al. (2015) — J Exp Med
• Ryu et al. (2023) — Cells
• Lee et al. (2023) — Adv Healthc Mater

Storage, Handling & Stability Guidelines

Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.

• Store sealed lyophilized material at -20°C.
• Maintain desiccated storage conditions to limit moisture exposure.
• Protect the vial from light during storage and handling.
• Use a validated laboratory SOP and the applicable lot/source record for any preparation or post-reconstitution handling.
• Use a validated laboratory SOP and the applicable lot/source record for any preparation or post-reconstitution handling.
• Maintain traceability between SKU PTD5, the received vial, internal inventory records, and any available analytical documentation.

The supplied data does not provide a validated reconstitution solvent, working concentration, post-reconstitution expiration interval, stability-study result, temperature-excursion tolerance, or packaging validation. Those values should not be inferred from unrelated peptide listings or informal protocol summaries.

Quality Assurance & Lab Verification

The Certificate of Analysis for this catalog item is pending. No provisional batch, assay, method, analyst, or release data is published in this product dossier. Check the Lab Verified archive for documentation status.