Tesamorelin
Tesamorelin from the Nexus Growth Hormone Secretagogues catalog, supplied for controlled in-vitro research workflows.
In stock: 2mg is in stock.
For in-vitro research use only. Not for human consumption.
Tesamorelin is a synthetic 44-amino acid GHRH analog with a trans-3-hexenoic acid group added to the N-terminus of native GHRH(1-44). This modification enhances metabolic stability. It stimulates the GHRH receptor, promoting endogenous GH synthesis and pulsatile release from the anterior pituitary.
No sequence is listed in the current catalog record for this product.
- CAS
- 218949-48-5
- MW
- 5135.9 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C221H366N72O67S
- Purity
- 99.51%
- Form
- Lyophilized powder
- Class
- Modified GHRH Analog
This lyophilized research material is commonly paired with bacteriostatic water for reconstitution workflows.
Browse bacteriostatic waterThe dossier.
Compound Overview
Tesamorelin is a synthetic GHRH analog composed of 44 amino acids, with a trans-3-hexenoic acid group added to the N-terminus of native GHRH(1-44). This modification enhances metabolic stability. In controlled research models, it stimulates the GHRH receptor and promotes endogenous GH synthesis and pulsatile release from the anterior pituitary.
Research Background & Published Literature
Clinical references describe Egrifta, the branded Tesamorelin product, as approved for HIV-associated lipodystrophy; Nexus supplies this research-grade Tesamorelin material strictly for in-vitro research only, and it is not approved for any human application. Published literature in New England Journal of Medicine and JAMA has examined Tesamorelin in relation to visceral adipose tissue, liver fat content, and GH-axis regulation.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
Storage, Handling & Stability Guidelines
Store lyophilized Tesamorelin at -20°C for long-term stability. After reconstitution with sterile diluent, keep research material refrigerated at 2–8°C and minimize freeze-thaw cycles by aliquoting working volumes according to your laboratory's standard operating procedures.
- Keep ambient-temperature handling time brief to help preserve compound integrity.
- Reseal vials promptly after each withdrawal to reduce moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Lab Verification
Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Compounds are supplied as lyophilized research material — follow the storage and reconstitution guidance on the product page and its Certificate of Analysis.
Compound details.
- CAS Number
- 218949-48-5
- Molecular Weight
- 5135.9 g/mol
- Molecular Formula
- C₂₂₁H₃₆₆N₇₂O₆₇S
- Class
- Modified GHRH Analog
- Purity
- ≥99% purity
- Physical Form
- Lyophilized powder
- Storage
- Store at -20°C (long term). Refrigerate after reconstitution.
Research context.
The branded clinical product Egrifta is approved for HIV-associated lipodystrophy in clinical use; This material is supplied strictly for in-vitro research use only and is not approved for any human application. Published in New England Journal of Medicine and JAMA. Studied for its effects on visceral adipose tissue, liver fat content, and GH-axis regulation.
Verification standard.
Independently verified Nexus Laboratory batches ship with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin context where applicable — verified by independent third-party laboratories and publicly archived; lots awaiting final documentation are labeled certificate pending instead of showing assay values. Review Nexus lab verification.
HPLC trace.
- HPLC purity
- 99.51%
- Retention time
- 18 min
- Batch
- NEX-TESAMORELIN-2026-0087
The full reverse-phase HPLC chromatogram, peak integration table, and mass-spectrometry identity confirmation for this batch are published on the certificate of analysis.
View certificate of analysis - batch NEX-TESAMORELIN-2026-0087- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
44-amino acid GHRH analog with trans-3-hexenoic acid modification
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: Tesamorelin
- Classification: Modified GHRH Analog
- Structural Description: 44-amino acid GHRH analog with trans-3-hexenoic acid modification
- CAS Number: 218949-48-5
- Molecular Weight: 5135.9 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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Tesamorelin research FAQ.
What is Tesamorelin used for in research?
Tesamorelin is supplied for controlled in-vitro research workflows in the Growth Hormone Secretagogues category. It is not labeled for human or veterinary use.
Is Tesamorelin HPLC verified?
Tesamorelin has a finalized Nexus Lab Verified record with 99.51% HPLC purity context in the current COA data.
Which Tesamorelin sizes are available?
Current Nexus variants include 2mg, 5mg, 10mg, 20mg.
Does Tesamorelin include a COA?
Yes. The current Nexus record links Tesamorelin to verified batch NEX-TESAMORELIN-2026-0087.