Tesamorelin
Tesamorelin from the Nexus Growth Hormone Secretagogues catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
Tesamorelin is a synthetic 44-amino acid GHRH analog with a trans-3-hexenoic acid group added to the N-terminus of native GHRH(1-44). This modification enhances metabolic stability. It stimulates the GHRH receptor, promoting endogenous GH synthesis and pulsatile release from the anterior pituitary.
No sequence is listed in the current catalog record for this product.
- CAS
- 218949-48-5
- MW
- 5135.9 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C221H366N72O67S
- Purity
- 99.51%
- Form
- Lyophilized powder
- Class
- Modified GHRH Analog
The dossier.
Compound Overview
Tesamorelin is a synthetic GHRH analog composed of 44 amino acids, with a trans-3-hexenoic acid group added to the N-terminus of native GHRH(1-44). This modification enhances metabolic stability. In controlled research models, it stimulates the GHRH receptor and promotes endogenous GH synthesis and pulsatile release from the anterior pituitary.
Research Background & Published Literature
Clinical references describe Egrifta, the branded Tesamorelin product, as approved for HIV-associated lipodystrophy; Nexus supplies this research-grade Tesamorelin material strictly for in-vitro research only, and it is not approved for any human application. Published literature in New England Journal of Medicine and JAMA has examined Tesamorelin in relation to visceral adipose tissue, liver fat content, and GH-axis regulation.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep ambient-temperature handling time brief to help preserve compound integrity.
- Reseal vials promptly after each withdrawal to reduce moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 218949-48-5
- Molecular Weight
- 5135.9 g/mol
- Molecular Formula
- C₂₂₁H₃₆₆N₇₂O₆₇S
- Class
- Modified GHRH Analog
Research context.
The branded clinical product Egrifta is approved for HIV-associated lipodystrophy in clinical use; This material is supplied strictly for in-vitro research use only and is not approved for any human application. Published in New England Journal of Medicine and JAMA. Studied for its effects on visceral adipose tissue, liver fat content, and GH-axis regulation.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.51%
- Retention time
- 18.00 min
- Observed mass
- 5135.78 Da
- Batch
- APX-2026-0414-T
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0414-T- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
44-amino acid GHRH analog with trans-3-hexenoic acid modification
Technical specifications.
- Product Name: Tesamorelin
- Classification: Modified GHRH Analog
- Structural Description: 44-amino acid GHRH analog with trans-3-hexenoic acid modification
- CAS Number: 218949-48-5
- Molecular Weight: 5135.9 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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Tesamorelin research FAQ.
What is Tesamorelin used for in research?
Tesamorelin is supplied for controlled in-vitro research workflows in the Growth Hormone Secretagogues category. It is not labeled for human or veterinary use.
Does Tesamorelin have a finalized analytical record?
Tesamorelin has a finalized Nexus Lab Verified record that reports 99.51% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which Tesamorelin variants are published?
Published Nexus variants include 2mg, 5mg, 10mg, 20mg.
Does Tesamorelin include a COA?
Yes. The current Nexus record links Tesamorelin to finalized batch APX-2026-0414-T.