VIP
VIP from the Nexus Sexual Health catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide that activates VPAC1 and VPAC2 receptors (class B GPCRs). It plays roles in vasodilation, smooth muscle relaxation, neuromodulation, circadian rhythm regulation, and immune signaling. Research examines its broad-spectrum effects across multiple organ systems.
No sequence is listed in the current catalog record for this product.
- CAS
- 37221-79-7
- MW
- 3326.82 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C147H237N43O43S
- Purity
- 99.58%
- Form
- Lyophilized powder
- Class
- Vasoactive Neuropeptide
The dossier.
Compound Overview
Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide described in research literature as an activator of VPAC1 and VPAC2 receptors (class B GPCRs). Controlled studies use VIP to examine vasodilation, smooth muscle relaxation, neuromodulation, circadian rhythm regulation, and immune signaling across multiple organ systems.
Research Background & Published Literature
VIP was discovered in 1970 by Said and Mutt, and the compound has since appeared in thousands of published studies, including work in Journal of Neuroimmunology, Endocrinology, and Peptides. In laboratory contexts, VIP remains a research tool for neuroendocrine, gastrointestinal, and immunological signaling studies.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep ambient-temperature handling windows brief to help preserve compound integrity.
- Limit moisture exposure by resealing vials promptly after each withdrawal.
- Wear appropriate personal protective equipment and follow institutional chemical safety protocols during all handling steps.
- Maintain traceability by labeling aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 37221-79-7
- Molecular Weight
- 3326.82 g/mol
- Molecular Formula
- C₁₄₇H₂₃₇N₄₃O₄₃S
- Class
- Vasoactive Neuropeptide
Research context.
Discovered in 1970 by Said and Mutt. Thousands of published studies in Journal of Neuroimmunology, Endocrinology, and Peptides. VIP is a key research tool in neuroendocrine, gastrointestinal, and immunological signaling studies.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.58%
- Retention time
- 14.80 min
- Observed mass
- 3325.25 Da
- Batch
- APX-2026-0417-V
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0417-V- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
Technical specifications.
- Product Name: VIP
- Classification: Vasoactive Neuropeptide
- Structural Description: 28-amino acid neuropeptide hormone
- CAS Number: 37221-79-7
- Molecular Weight: 3326.82 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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VIP research FAQ.
What is VIP used for in research?
VIP is supplied for controlled in-vitro research workflows in the Sexual Health category. It is not labeled for human or veterinary use.
Does VIP have a finalized analytical record?
VIP has a finalized Nexus Lab Verified record that reports 99.58% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which VIP variants are published?
Published Nexus variants include 5mg, 10mg.
Does VIP include a COA?
Yes. The current Nexus record links VIP to finalized batch APX-2026-0417-V.