PT-141
PT-141 from the Nexus Sexual Health catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
PT-141 (Bremelanotide) is a cyclic heptapeptide metabolite of Melanotan II. It activates melanocortin receptors MC3R and MC4R with relative selectivity over MC1R. Research focuses on its central nervous system melanocortin signaling, particularly in hypothalamic pathways regulating sexual arousal and behavior.
No sequence is listed in the current catalog record for this product.
- CAS
- 189691-06-3
- MW
- 1025.18 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C50H68N14O10
- Purity
- 99.74%
- Form
- Lyophilized powder
- Class
- Melanocortin Receptor Agonist (MC3R/MC4R Selective)
The dossier.
Compound Overview
PT-141 (Bremelanotide) is a cyclic heptapeptide metabolite of Melanotan II. Research literature describes activation at melanocortin receptors MC3R and MC4R with relative selectivity over MC1R. In controlled laboratory models, PT-141 is studied for central nervous system melanocortin signaling, particularly hypothalamic pathways associated with sexual arousal and behavior.
Research Background & Published Literature
Bremelanotide appears in regulated clinical literature under separate product contexts; Nexus PT-141 is not supplied for clinical, human, veterinary, therapeutic, diagnostic, treatment, or disease-related use. Research publications in journals such as Journal of Sexual Medicine and Journal of Urology examine central nervous system melanocortin signaling as distinct from peripheral melanogenesis pathways.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
- Kingsberg et al. (2019) — Obstet Gynecol
- Althof et al. (2019) — J Sex Med
- Cipriani et al. (2023) — Expert Opin Pharmacother
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep ambient-temperature exposure as brief as practical during handling to support compound integrity.
- Reseal vials promptly after each withdrawal to limit moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 189691-06-3
- Molecular Weight
- 1025.18 g/mol
- Molecular Formula
- C₅₀H₆₈N₁₄O₁₀
- Class
- Melanocortin Receptor Agonist (MC3R/MC4R Selective)
Research context.
The branded clinical product Vyleesi is approved for hypoactive sexual desire disorder (HSDD) in adult women; This material is supplied strictly for in-vitro research use only. Published in Journal of Sexual Medicine and Journal of Urology. Research examines CNS melanocortin signaling as distinct from peripheral melanogenesis pathways.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.74%
- Retention time
- 9.00 min
- Observed mass
- 1025.26 Da
- Batch
- APX-2026-0401-B
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0401-B- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
Cyclic 7-amino acid peptide (Bremelanotide), metabolite of Melanotan II
Technical specifications.
- Product Name: PT-141 10mg
- Classification: Melanocortin Receptor Agonist (MC3R/MC4R Selective)
- Structural Description: Cyclic 7-amino acid peptide (Bremelanotide), metabolite of Melanotan II
- CAS Number: 189691-06-3
- Molecular Weight: 1025.18 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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PT-141 research FAQ.
What is PT-141 used for in research?
PT-141 is supplied for controlled in-vitro research workflows in the Sexual Health category. It is not labeled for human or veterinary use.
Does PT-141 have a finalized analytical record?
PT-141 has a finalized Nexus Lab Verified record that reports 99.74% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which PT-141 variants are published?
Published Nexus variants include 10mg.
Does PT-141 include a COA?
Yes. The current Nexus record links PT-141 to finalized batch APX-2026-0401-B.