5-amino-1mq
5-amino-1mq from the Nexus Mitochondrial & Energy catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
Certificate pending — assay values withheld
Final assay values publish here once independent documentation is available. See the verification process.
For in-vitro research use only. Not for human consumption.
5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that methylates nicotinamide using SAM as a methyl donor. By inhibiting NNMT, 5-Amino-1MQ may increase intracellular NAD+ levels and SAM availability, linking it to sirtuin activity, methylation capacity, and adipocyte differentiation research.
No sequence is listed in the current catalog record for this product.
- CAS
- 685079-15-6
- MW
- 159.21 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C10H11N2
- Purity
- Certificate pending
- Form
- Lyophilized powder
- Class
- NNMT Inhibitor / Metabolic Research Compound
The dossier.
Compound Overview
5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme responsible for methylating nicotinamide with SAM as the methyl donor. In controlled research models, NNMT inhibition by 5-Amino-1MQ may increase intracellular NAD+ levels and SAM availability, making the compound relevant to investigations involving sirtuin activity, methylation capacity, and adipocyte differentiation.
Research Background & Published Literature
5-Amino-1MQ has been reported in Biochemical Pharmacology and studied by researchers at University of Texas Medical Branch. NNMT is examined as a target in metabolic disease and cancer research, and 5-Amino-1MQ is frequently used as a pharmacological tool compound in that research context.
For more detail on mechanism of action, signaling pathways, and controlled experimental applications, researchers can review the peer-reviewed literature below:
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Limit ambient-temperature handling time to help maintain compound integrity.
- Reseal vials promptly after each withdrawal to reduce moisture exposure.
- Wear appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
The Certificate of Analysis for this catalog item is pending. No provisional batch, assay, method, analyst, or release data is published in this product dossier. Check the Lab Verified archive for documentation status.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 685079-15-6
- Molecular Weight
- 159.21 g/mol
- Molecular Formula
- C₁₀H₁₁N₂
- Class
- NNMT Inhibitor / Metabolic Research Compound
Research context.
Published in Biochemical Pharmacology and by researchers at University of Texas Medical Branch. NNMT has emerged as a target in metabolic disease and cancer research, with 5-Amino-1MQ as a primary pharmacological tool compound.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Certificate status.
Finalized independent certificate documentation is pending for this catalog record. Measurement details remain withheld until the certificate is available.
- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
Small molecule NNMT inhibitor (non-peptide), 5-amino-1-methylquinolinium
Technical specifications.
- Product Name: 5-Amino-1MQ
- Classification: NNMT Inhibitor / Metabolic Research Compound
- Structural Description: Small molecule NNMT inhibitor (non-peptide), 5-amino-1-methylquinolinium
- CAS Number: 685079-15-6
- Molecular Weight: 159.21 Da
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: See product label for form details
- Intended Use: In-vitro research use only — not for human consumption
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5-amino-1mq research FAQ.
What is 5-amino-1mq used for in research?
5-amino-1mq is supplied for controlled in-vitro research workflows in the Mitochondrial & Energy category. It is not labeled for human or veterinary use.
Does 5-amino-1mq have a finalized analytical record?
5-amino-1mq is listed with certificate-pending status until a finalized lot-specific COA record is available.
Which 5-amino-1mq variants are published?
Published Nexus variants include 5mg, 10mg, 50mg.
Does 5-amino-1mq include a COA?
The current Nexus record marks 5-amino-1mq as certificate pending; finalized assay values are not shown until lot-specific documentation is available.