NAD+
NAD+ from the Nexus Longevity & Cellular Health catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme present in all living cells. It serves as an electron carrier in metabolic redox reactions (glycolysis, TCA cycle, oxidative phosphorylation) and as a substrate for sirtuin deacetylases (SIRT1-7), PARPs, and CD38. Research focuses on its role in aging, DNA repair, and mitochondrial function.
No sequence is listed in the current catalog record for this product.
- CAS
- 53-84-9
- MW
- 663.43 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C21H27N7O14P2
- Purity
- 99.31%
- Form
- Lyophilized powder
- Class
- Coenzyme / Redox Cofactor
The dossier.
Compound Overview
NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme present in all living cells. In experimental biology, it is studied as an electron carrier in metabolic redox reactions (glycolysis, TCA cycle, oxidative phosphorylation) and as a substrate for sirtuin deacetylases (SIRT1-7), PARPs, and CD38. Research attention commonly centers on aging, DNA repair, and mitochondrial function.
Research Background & Published Literature
NAD+ biology remains one of the most active areas in aging and metabolism research, with published work appearing in Nature, Science, Cell, and Cell Metabolism. Major laboratory research themes include NAD+ decline with age, sirtuin-mediated signaling, and metabolic pathway regulation.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
- Verdin (2015) — Science
- Covarrubias et al. (2021) — Nat Rev Mol Cell Biol
- Lautrup et al. (2019) — Cell Metab
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep ambient-temperature handling time as short as practical to support compound integrity.
- Reseal vials promptly after each withdrawal to limit moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 53-84-9
- Molecular Weight
- 663.43 g/mol
- Molecular Formula
- C₂₁H₂₇N₇O₁₄P₂
- Class
- Coenzyme / Redox Cofactor
Research context.
NAD+ biology is one of the most active areas in aging and metabolism research. Published in Nature, Science, Cell, and Cell Metabolism. Key research focuses on NAD+ decline with age, sirtuin-mediated signaling, and metabolic pathway regulation.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.31%
- Retention time
- 6.00 min
- Observed mass
- 663.58 Da
- Batch
- APX-2026-0315-N
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0315-N- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
Nicotinamide adenine dinucleotide (oxidized form), essential coenzyme
Technical specifications.
- Product Name: NAD+
- Classification: Coenzyme / Redox Cofactor
- Structural Description: Nicotinamide adenine dinucleotide (oxidized form), essential coenzyme
- CAS Number: 53-84-9
- Molecular Weight: 663.43 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: See product label for form details
- Intended Use: In-vitro research use only — not for human consumption
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NAD+ research FAQ.
What is NAD+ used for in research?
NAD+ is supplied for controlled in-vitro research workflows in the Longevity & Cellular Health category. It is not labeled for human or veterinary use.
Does NAD+ have a finalized analytical record?
NAD+ has a finalized Nexus Lab Verified record that reports 99.31% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which NAD+ variants are published?
Published Nexus variants include 100mg, 250mg, 500mg, 1000mg.
Does NAD+ include a COA?
Yes. The current Nexus record links NAD+ to finalized batch APX-2026-0315-N.