Matrixyl

Compound Overview

Research Use Only. Not for Human Consumption.

Matrixyl is supplied by Nexus as a 10mg research catalog variant under SKU MA10. The supplied research record identifies Matrixyl as a palmitoylated cosmetic signal peptide and specifies the underlying molecule as palmitoyl pentapeptide-4, commonly written as Pal-KTTKS.

The source data describes Matrixyl as a cosmetic lipopeptide used in extracellular-matrix and dermal-fibroblast research workflows. That classification is included here only as research-context terminology. It does not imply human use, cosmetic application, topical use, therapeutic use, disease-related use, veterinary use, or dosing guidance.

• Product: Matrixyl
• Available Research Size: 10mg
• SKU: MA10
• Catalog Category: Cosmetic & Skin
• Classification: Palmitoylated cosmetic signal peptide
• Structural Description: Palmitoyl pentapeptide-4, commonly written Pal-KTTKS, a palmitic-acid conjugated collagen-fragment signal peptide.
• Sequence: KTTKS
• Palmitoylated Sequence Display: Pal-Lys-Thr-Thr-Lys-Ser
• CAS Number: 214047-00-4
• Molecular Weight: 802.05 g/mol
• Molecular Formula: C₃₉H₇₅N₇O₁₀
• Physical Form: Lyophilized powder
• Use: For in-vitro research use only. Not for human consumption.

Research Background & Published Literature

The supplied research background notes an important labeling boundary: Matrixyl is a trade name, so final labeling should use the chemical name palmitoyl pentapeptide-4 and verify that the material corresponds to the Pal-KTTKS molecule rather than another Matrixyl-family peptide. Nexus applies that distinction by identifying this catalog item as palmitoyl pentapeptide-4 / Pal-KTTKS within the product record.

The structural description in the source record defines the compound as a palmitic-acid conjugated collagen-fragment signal peptide. The supplied sequence field lists KTTKS, while the sequence display field lists Pal-Lys-Thr-Thr-Lys-Ser. In practical catalog documentation, those two fields should be read together: the peptide sequence is KTTKS, and the Matrixyl molecule described here is the palmitoylated form, Pal-KTTKS.

The research file does not provide peer-reviewed citation details such as PubMed identifiers, DOI identifiers, journal names, publication dates, assay systems, cell models, exposure conditions, analytical methods, or quantitative endpoints. This section therefore stays at the level of compound identity, nomenclature, and source-record boundaries instead of adding mechanistic or outcome claims not present in the supplied data.

The supplied source list includes the following background references:

Those links are included because they appear in the supplied research record. This product description does not expand beyond the facts provided in the Nexus product and research data.

Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:

• Robinson et al. (2005) — Int J Cosmet Sci
• Choi et al. (2014) — Biomol Ther (Seoul)

Storage, Handling & Stability Guidelines

Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.

• Store lyophilized material at -20°C.
• Keep the material desiccated during storage.
• Protect stored material from light exposure.
• Use a validated laboratory SOP and the applicable lot/source record for any preparation or post-reconstitution handling.
• Use a validated laboratory SOP and the applicable lot/source record for any preparation or post-reconstitution handling.
• Maintain research records that connect aliquots to the original product name, SKU, and received lot documentation.

The supplied record does not specify a validated reconstitution solvent, target concentration, post-reconstitution expiration interval, container compatibility profile, acceptable freeze-thaw count, or formal stability-study result. Those details should be established from current lot documentation or a laboratory-validated protocol, not extrapolated from adjacent compounds.

Quality Assurance & Lab Verification

The Certificate of Analysis for this catalog item is pending. No provisional batch, assay, method, analyst, or release data is published in this product dossier. Check the Lab Verified archive for documentation status.