snap-8
snap-8 from the Nexus Cosmetic & Skin catalog, supplied for controlled in-vitro research workflows.
In stock: 10mg is in stock.
For in-vitro research use only. Not for human consumption.
Snap-8 (Acetyl Octapeptide-3) is a synthetic peptide studied for SNARE complex modulation through competition with SNAP-25 for binding. The SNARE complex mediates vesicular neurotransmitter release, and this pathway makes Snap-8 relevant to controlled in-vitro work examining neuromuscular signaling and expression-related skin research models.
snap-8 definition
SNAP-8 is an acetylated 8-amino-acid synthetic peptide derived from the N-terminal sequence of the SNARE-complex protein SNAP-25. Research models examine its interaction with SNARE-complex assembly in research-context models of neurotransmitter-release pharmacology. Cosmetic and signaling research applications. Research use only. Independently verified Nexus lots publish a Certificate of Analysis documenting HPLC purity, mass spectrometry identity, and endotoxin screening; pending lots are labeled certificate pending.
No sequence is listed in the current catalog record for this product.
- CAS
- 868844-74-0
- MW
- 1075.16 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- Not listed
- Purity
- Not listed
- Form
- Not listed
- Class
- Cosmetic & Skin
This lyophilized research material is commonly paired with bacteriostatic water for reconstitution workflows.
Browse bacteriostatic waterThe dossier.
Compound Overview
Snap-8 (Acetyl Octapeptide-3) is a synthetic peptide studied for SNARE complex modulation through competition with SNAP-25 for binding. The SNARE complex mediates vesicular neurotransmitter release, and this pathway makes Snap-8 relevant to controlled in-vitro work examining neuromuscular signaling and expression-related skin research models.
Research Background & Published Literature
Lipotec originally developed Snap-8. Published work in the International Journal of Cosmetic Science evaluates experimental effects on catecholamine release and neuromuscular junction signaling in cell culture models.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
Storage, Handling & Stability Guidelines
For long-term stability, keep lyophilized Snap-8 stored at -20°C. After reconstitution with sterile diluent, refrigerate at 2–8°C and reduce repeated freeze-thaw exposure by aliquoting working volumes according to your laboratory's standard operating procedures.
- Keep ambient-temperature handling time as short as practical to support compound integrity.
- Reseal vials promptly after each withdrawal to limit moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Lab Verification
Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Compounds are supplied as lyophilized research material — follow the storage and reconstitution guidance on the product page and its Certificate of Analysis.
Compound details.
- CAS Number
- 868844-74-0
- Molecular Weight
- 1075.2 g/mol
- Class
- Acetylated octapeptide (SNAP-25-derived)
- Sequence length
- 8 residues, N-terminally acetylated
Research context.
Studied in preclinical research models examining SNARE-complex pharmacology, neurotransmitter release research, and cosmetic research applications focused on dermal-fibroblast signaling models. Research use only.
Verification standard.
Independently verified Nexus Laboratory batches ship with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin context where applicable — verified by independent third-party laboratories and publicly archived; lots awaiting final documentation are labeled certificate pending instead of showing assay values. Review Nexus lab verification.
HPLC trace.
- HPLC purity
- See COA
- Retention time
- See COA
- Batch
- NEX-SNAP-8-2026-0082
The full reverse-phase HPLC chromatogram, peak integration table, and mass-spectrometry identity confirmation for this batch are published on the certificate of analysis.
View certificate of analysis - batch NEX-SNAP-8-2026-0082- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
Static molecular fallback shown because this catalog record does not include a sequence suitable for the amino-acid viewer.
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snap-8 research FAQ.
What is snap-8 used for in research?
snap-8 is supplied for controlled in-vitro research workflows in the Cosmetic & Skin category. It is not labeled for human or veterinary use.
Is snap-8 HPLC verified?
snap-8 has a finalized Nexus Lab Verified record with batch-specific HPLC purity context in the current COA data.
Which snap-8 sizes are available?
Current Nexus variants include 10mg.
Does snap-8 include a COA?
Yes. The current Nexus record links snap-8 to verified batch NEX-SNAP-8-2026-0082.