GHK-CU
GHK-CU from the Nexus Cosmetic & Skin catalog, supplied for controlled in-vitro research workflows.
In stock: 50mg is in stock.
For in-vitro research use only. Not for human consumption.
GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. The copper(II) complex modulates extracellular matrix remodeling through stimulation of collagen synthesis, glycosaminoglycan production, and growth factor signaling. Research also examines its antioxidant activity through superoxide dismutase-like effects.
No sequence is listed in the current catalog record for this product.
- CAS
- 89030-95-5
- MW
- 402.92 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C14H23CuN6O4
- Purity
- 99.76%
- Form
- Lyophilized powder
- Class
- Copper Peptide Complex
This lyophilized research material is commonly paired with bacteriostatic water for reconstitution workflows.
Browse bacteriostatic waterThe dossier.
Compound Overview
GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. In laboratory literature, the copper(II) complex is studied for extracellular matrix remodeling pathways associated with collagen synthesis, glycosaminoglycan production, and growth factor signaling. Additional research evaluates antioxidant activity through superoxide dismutase-like effects.
Research Background & Published Literature
GHK-Cu was discovered by Dr. Loren Pickart and has been evaluated extensively in dermatological and tissue remodeling research contexts. Publications in Journal of Biomaterials Science and Life Sciences have reported experimental findings related to fibroblast behavior, ECM production, and antioxidant defense pathways.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
- Pickart et al. (2015) — Biomed Res Int
- Pickart (2008) — J Biomater Sci Polym Ed
- Pickart et al. (2017) — Brain Sci
Storage, Handling & Stability Guidelines
For long-term stability, keep lyophilized GHK-Cu stored at -20°C. After reconstitution with sterile diluent, refrigerate at 2–8°C and reduce repeated freeze-thaw exposure by aliquoting working volumes according to your laboratory's standard operating procedures.
- Keep ambient-temperature handling time as short as practical to support compound integrity.
- Reseal vials promptly after each withdrawal to limit moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Lab Verification
Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Compounds are supplied as lyophilized research material — follow the storage and reconstitution guidance on the product page and its Certificate of Analysis.
Compound details.
- CAS Number
- 89030-95-5
- Molecular Weight
- 402.92 g/mol
- Molecular Formula
- C₁₄H₂₃CuN₆O₄
- Class
- Copper Peptide Complex
- Purity
- ≥99% purity
- Physical Form
- Lyophilized powder
- Storage
- Store at -20°C (long term). Refrigerate after reconstitution.
Research context.
Discovered by Dr. Loren Pickart, GHK-Cu has been studied extensively in dermatological and tissue remodeling research. Published studies in Journal of Biomaterials Science and Life Sciences have documented its effects on fibroblast behavior, ECM production, and antioxidant defense pathways.
Verification standard.
Independently verified Nexus Laboratory batches ship with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin context where applicable — verified by independent third-party laboratories and publicly archived; lots awaiting final documentation are labeled certificate pending instead of showing assay values. Review Nexus lab verification.
HPLC trace.
- HPLC purity
- 99.76%
- Retention time
- 3.4 min
- Batch
- NEX-GHK-CU-2026-0035
The full reverse-phase HPLC chromatogram, peak integration table, and mass-spectrometry identity confirmation for this batch are published on the certificate of analysis.
View certificate of analysis - batch NEX-GHK-CU-2026-0035- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
Tripeptide-copper complex (Glycyl-L-histidyl-L-lysine:copper(II))
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: GHK-Cu
- Classification: Copper Peptide Complex
- Structural Description: Tripeptide-copper complex (Glycyl-L-histidyl-L-lysine:copper(II))
- CAS Number: 89030-95-5
- Molecular Weight: 402.92 g/mol (peptide + copper complex)
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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Research notes.
GHK-CU research FAQ.
What is GHK-CU used for in research?
GHK-CU is supplied for controlled in-vitro research workflows in the Cosmetic & Skin category. It is not labeled for human or veterinary use.
Is GHK-CU HPLC verified?
GHK-CU has a finalized Nexus Lab Verified record with 99.76% HPLC purity context in the current COA data.
Which GHK-CU sizes are available?
Current Nexus variants include 50mg, 100mg.
Does GHK-CU include a COA?
Yes. The current Nexus record links GHK-CU to verified batch NEX-GHK-CU-2026-0035.