GHK-CU
GHK-CU from the Nexus Cosmetic & Skin catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. The copper(II) complex modulates extracellular matrix remodeling through stimulation of collagen synthesis, glycosaminoglycan production, and growth factor signaling. Research also examines its antioxidant activity through superoxide dismutase-like effects.
No sequence is listed in the current catalog record for this product.
- CAS
- 89030-95-5
- MW
- 402.92 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C14H23CuN6O4
- Purity
- 99.76%
- Form
- Lyophilized powder
- Class
- Copper Peptide Complex
The dossier.
Compound Overview
GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. In laboratory literature, the copper(II) complex is studied for extracellular matrix remodeling pathways associated with collagen synthesis, glycosaminoglycan production, and growth factor signaling. Additional research evaluates antioxidant activity through superoxide dismutase-like effects.
Research Background & Published Literature
GHK-Cu was discovered by Dr. Loren Pickart and has been evaluated extensively in dermatological and tissue remodeling research contexts. Publications in Journal of Biomaterials Science and Life Sciences have reported experimental findings related to fibroblast behavior, ECM production, and antioxidant defense pathways.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
- Pickart et al. (2015) — Biomed Res Int
- Pickart (2008) — J Biomater Sci Polym Ed
- Pickart et al. (2017) — Brain Sci
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep ambient-temperature handling time as short as practical to support compound integrity.
- Reseal vials promptly after each withdrawal to limit moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 89030-95-5
- Molecular Weight
- 402.92 g/mol
- Molecular Formula
- C₁₄H₂₃CuN₆O₄
- Class
- Copper Peptide Complex
Research context.
Discovered by Dr. Loren Pickart, GHK-Cu has been studied extensively in dermatological and tissue remodeling research. Published studies in Journal of Biomaterials Science and Life Sciences have documented its effects on fibroblast behavior, ECM production, and antioxidant defense pathways.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.76%
- Retention time
- 3.40 min
- Observed mass
- 401.99 Da
- Batch
- APX-2026-0313-G
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0313-G- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
Tripeptide-copper complex (Glycyl-L-histidyl-L-lysine:copper(II))
Technical specifications.
- Product Name: GHK-Cu
- Classification: Copper Peptide Complex
- Structural Description: Tripeptide-copper complex (Glycyl-L-histidyl-L-lysine:copper(II))
- CAS Number: 89030-95-5
- Molecular Weight: 402.92 g/mol (peptide + copper complex)
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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Research notes.
GHK-CU research FAQ.
What is GHK-CU used for in research?
GHK-CU is supplied for controlled in-vitro research workflows in the Cosmetic & Skin category. It is not labeled for human or veterinary use.
Does GHK-CU have a finalized analytical record?
GHK-CU has a finalized Nexus Lab Verified record that reports 99.76% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which GHK-CU variants are published?
Published Nexus variants include 50mg, 100mg.
Does GHK-CU include a COA?
Yes. The current Nexus record links GHK-CU to finalized batch APX-2026-0313-G.