MT-2 (Melanotan 2 Acetate)
MT-2 (Melanotan 2 Acetate) from the Nexus Tanning & Pigmentation catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
Melanotan II is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH). It is a non-selective agonist of melanocortin receptors MC1R through MC5R. Research interest centers on its activation of MC1R (melanogenesis), MC3R and MC4R (metabolic and appetite regulation), and related neuroendocrine signaling.
MT-2 (Melanotan 2 Acetate) definition
MT-2 (Melanotan II) is a synthetic cyclic heptapeptide alpha-melanocyte-stimulating hormone (α-MSH) analog with broader melanocortin-receptor selectivity than MT-1. Research models examine its agonism across MC1R, MC3R, MC4R, and MC5R, supporting comparative pharmacology research on melanocortin pathway signaling. Research use only.
No sequence is listed in the current catalog record for this product.
- CAS
- 121062-08-6
- MW
- 1024.18 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C50H69N15O9
- Purity
- 99.56%
- Form
- Lyophilized powder
- Class
- Melanocortin Receptor Agonist
The dossier.
Compound Overview
Melanotan II, also referenced as MT-2, is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH). Research literature describes it as a non-selective agonist of melanocortin receptors MC1R through MC5R. Laboratory interest commonly focuses on MC1R activation in melanogenesis models, MC3R and MC4R involvement in metabolic and appetite regulation research, and related neuroendocrine signaling pathways.
Research Background & Published Literature
Originally developed at the University of Arizona, Melanotan II has been examined in melanogenesis, photoprotection research, and melanocortin signaling studies. Published work includes investigations into melanocortin receptor subtype selectivity and downstream cAMP signaling cascades.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
- Al-Obeidi et al. (1989) — J Med Chem
- Dorr et al. (1996) — Life Sci
- Ückert et al. (2014) — Expert Opin Investig Drugs
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep ambient-temperature exposure as brief as practical during handling to support compound integrity.
- Reseal vials promptly after each withdrawal to limit moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 121062-08-6
- Molecular Weight
- 1024.18 g/mol
- Class
- Cyclic alpha-MSH analog
- Sequence length
- 7 residues (cyclized)
- Receptor targets
- MC1R + MC3R + MC4R + MC5R
Research context.
Studied in preclinical research models examining broad-spectrum melanocortin receptor pharmacology, pigmentation pathway research, and side-by-side research with MT-1 for receptor-selectivity comparison. Research use only.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.56%
- Retention time
- 10.40 min
- Observed mass
- 1024.23 Da
- Batch
- APX-2026-0322-M
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0322-M- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
Technical specifications.
- Product Name: Melanotan II 10mg
- Classification: Melanocortin Receptor Agonist
- Structural Description: Cyclic 7-amino acid peptide analog of α-MSH
- CAS Number: 121062-08-6
- Molecular Weight: 1024.18 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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MT-2 (Melanotan 2 Acetate) research FAQ.
What is MT-2 (Melanotan 2 Acetate) used for in research?
MT-2 (Melanotan 2 Acetate) is supplied for controlled in-vitro research workflows in the Tanning & Pigmentation category. It is not labeled for human or veterinary use.
Does MT-2 (Melanotan 2 Acetate) have a finalized analytical record?
MT-2 (Melanotan 2 Acetate) has a finalized Nexus Lab Verified record that reports 99.56% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which MT-2 (Melanotan 2 Acetate) variants are published?
Published Nexus variants include 5mg, 10mg.
Does MT-2 (Melanotan 2 Acetate) include a COA?
Yes. The current Nexus record links MT-2 (Melanotan 2 Acetate) to finalized batch APX-2026-0322-M.