For in-vitro research use only. Not for human consumption.
MT-1
Melanotan I (afamelanotide) is a linear tridecapeptide analog of α-melanocyte-stimulating hormone. It demonstrates selectivity for the MC1R receptor compared to other melanocortin receptor subtypes, making it a valuable tool for studying melanogenesis signaling specifically through MC1R-mediated pathways.
MT-1 definition
MT-1 is a synthetic 13-amino-acid alpha-melanocyte-stimulating hormone (α-MSH) analog containing nor-leucine at position 4 and D-phenylalanine at position 7. Research models examine its selective agonism at melanocortin receptors (particularly MC1R) and its role as a research-context comparator to MT-2 (melanotan II) for melanocortin selectivity studies. Research use only. Supplied by Nexus Laboratory with batch-level certificate of analysis documenting HPLC purity, mass spectrometry identity, and endotoxin screening.
No sequence is listed in the current catalog record for this product.
- CAS
- 75921-69-6
- MW
- 1646.85 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C78H111N21O19
- Purity
- 99.82%
- Form
- Lyophilized powder
- Class
- MC1R-Selective Melanocortin Agonist
Reconstitution calculator
Estimate vial concentration and aliquot volume from the selected vial mass, solvent volume, and target research amount.
Calculations are for lab planning only and do not replace the product COA, protocol requirements, or qualified professional review. Confirm solvent compatibility before use.
Compound details.
- CAS Number
- 75921-69-6
- Molecular Weight
- 1646.85 g/mol
- Class
- Linear alpha-MSH analog
- Sequence length
- 13 residues
- Primary research target
- MC1R (with secondary activity at MC3/4/5)
Research context.
Studied in preclinical research models examining melanocortin-1 receptor pharmacology, melanogenesis pathway research, and receptor-selectivity comparison against MT-2. Research use only.
Verification standard.
Every Nexus Laboratory batch ships with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin screening — verified by third-party laboratory testing and publicly archived. Review Nexus lab verification.
MT-1 is part of the Nexus Tanning & Pigmentation catalog. Melanocortin and pigmentation research peptides. Each listed variant is priced from the consolidated Nexus catalog and intended for qualified research use only.
TODO-COPY: replace with real compound-specific narrative.
The chemistry.
Linear 13-amino acid peptide analog of α-MSH (also known as Afamelanotide)
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: Melanotan I 10mg
- Classification: MC1R-Selective Melanocortin Agonist
- Structural Description: Linear 13-amino acid peptide analog of α-MSH (also known as Afamelanotide)
- CAS Number: 75921-69-6
- Molecular Weight: 1646.85 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
HPLC trace preview.
Related research compounds
Same category, mechanism overlap, and common research stack pairings.
MT-1 research FAQ.
What is MT-1 used for in research?
MT-1 is supplied for controlled in-vitro research workflows in the Tanning & Pigmentation category. It is not labeled for human or veterinary use.
Is MT-1 HPLC verified?
MT-1 is listed with Nexus lab verification. Current catalog records show 99.82% purity context where batch COA data is available.
Which MT-1 sizes are available?
Current Nexus variants include 10mg.
Does MT-1 include a COA?
Yes. The current Nexus record links MT-1 to batch NEX-MT-1-2026-0056.