KPV
KPV from the Nexus Healing & Recovery catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
KPV is the C-terminal tripeptide fragment (Lys-Pro-Val) of alpha-melanocyte stimulating hormone (α-MSH). Despite lacking melanocortin receptor binding, KPV retains anti-inflammatory signaling through NF-κB pathway inhibition and PGE2 reduction. Research examines its immunomodulatory properties independent of melanocortin receptors.
No sequence is listed in the current catalog record for this product.
- CAS
- 67727-97-3
- MW
- 342.43 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C16H30N4O4
- Purity
- 99.45%
- Form
- Lyophilized powder
- Class
- Anti-Inflammatory Tripeptide / α-MSH Fragment
The dossier.
Compound Overview
KPV is the C-terminal tripeptide fragment (Lys-Pro-Val) of alpha-melanocyte stimulating hormone (α-MSH). Although it does not bind melanocortin receptors, KPV is studied for anti-inflammatory signaling associated with NF-κB pathway inhibition and PGE2 reduction. Research literature evaluates its immunomodulatory properties apart from melanocortin receptor activity.
Research Background & Published Literature
KPV appears in published work from Annals of the New York Academy of Sciences and FEBS Letters. Controlled research has examined the tripeptide in inflammatory bowel disease models, intestinal inflammation studies, and immune modulation experiments.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
- Dalmasso et al. (2008) — Gastroenterology
- Viennois et al. (2016) — Cell Mol Gastroenterol Hepatol
- Xiao et al. (2017) — Mol Ther
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep ambient-temperature handling time as short as practical to support compound integrity.
- Reseal vials promptly after each withdrawal to reduce moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 67727-97-3
- Molecular Weight
- 342.43 g/mol
- Molecular Formula
- C₁₆H₃₀N₄O₄
- Class
- Anti-Inflammatory Tripeptide / α-MSH Fragment
Research context.
Published in Annals of the New York Academy of Sciences and FEBS Letters. KPV has been studied in inflammatory bowel disease models, intestinal inflammation, and immune modulation research.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.45%
- Retention time
- 4.00 min
- Observed mass
- 342.46 Da
- Batch
- APX-2026-0318-K
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0318-K- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
Technical specifications.
- Product Name: KPV
- Classification: Anti-Inflammatory Tripeptide / α-MSH Fragment
- Structural Description: C-terminal tripeptide of alpha-MSH (Lys-Pro-Val)
- CAS Number: 67727-97-3
- Molecular Weight: 342.43 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
Related research compounds
Comparable catalog records with published variants and certificate status.
- Healing & RecoveryVerified batchBPC 157PriceFrom $30.99Formats4 sizes
Compare size options, price, and certificate status before opening the product record.
CAS 137525-51-0View product - Healing & RecoveryCertificate pendingBPC 157 10mg+GHK-CU 50mg+TB500 10mg+KPV 10mgPrice$210.99Formats1 size
Compare size options, price, and certificate status before opening the product record.
View product - Healing & RecoveryVerified batchLL37Price$81.99Formats1 size
Compare size options, price, and certificate status before opening the product record.
CAS 154947-66-7View product - Healing & RecoveryVerified batchThymosin Alpha-1PriceFrom $42.99Formats3 sizes
Compare size options, price, and certificate status before opening the product record.
CAS 62304-98-7View product - Healing & RecoveryVerified batchTB500 (Thymosin B4 Acetate)PriceFrom $30.99Formats4 sizes
Compare size options, price, and certificate status before opening the product record.
CAS 77591-33-4View product
KPV research FAQ.
What is KPV used for in research?
KPV is supplied for controlled in-vitro research workflows in the Healing & Recovery category. It is not labeled for human or veterinary use.
Does KPV have a finalized analytical record?
KPV has a finalized Nexus Lab Verified record that reports 99.45% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which KPV variants are published?
Published Nexus variants include 5mg, 10mg.
Does KPV include a COA?
Yes. The current Nexus record links KPV to finalized batch APX-2026-0318-K.