AOD9604
AOD9604 from the Nexus Specialty Research catalog, supplied for controlled in-vitro research workflows.
In stock: 2mg is in stock.
For in-vitro research use only. Not for human consumption.
AOD9604 is a modified 16-amino acid peptide fragment corresponding to the C-terminal region of human growth hormone (amino acids 176-191). It was specifically designed to isolate the lipolytic activity of hGH while excluding somatotropic effects. Research has examined its interaction with beta-3 adrenergic receptor signaling and fat metabolism pathways.
No sequence is listed in the current catalog record for this product.
- CAS
- 221231-10-3
- MW
- 1815.08 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C78H123N23O23S2
- Purity
- 99.63%
- Form
- Lyophilized powder
- Class
- Modified hGH Fragment
This lyophilized research material is commonly paired with bacteriostatic water for reconstitution workflows.
Browse bacteriostatic waterThe dossier.
Compound Overview
AOD9604 is a modified 16-amino acid peptide fragment that corresponds to the C-terminal region of human growth hormone (amino acids 176-191). The compound was designed to separate the lipolytic activity associated with hGH from somatotropic effects. Laboratory research has evaluated AOD9604 in relation to beta-3 adrenergic receptor signaling and fat metabolism pathways.
Research Background & Published Literature
AOD9604 was originally developed by Metabolic Pharmaceuticals and studied at Monash University as part of adipose tissue metabolism research. Published investigations have examined lipogenesis inhibition and lipolysis stimulation in adipocyte models. A published regulatory background note states that AOD9604 received GRAS (Generally Recognized as Safe) status from the FDA as a food ingredient in 2011; Nexus does not market this catalog item for food, human, veterinary, or therapeutic use.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
Storage, Handling & Stability Guidelines
Store lyophilized AOD9604 at -20°C. Because AOD9604 is a relatively small 16-amino acid peptide, the lyophilized material has good stability when kept under appropriate storage conditions. After reconstitution, store material at 2–8°C and use within 14 days.
- Keep ambient-temperature handling time as short as practical to support compound integrity.
- Reseal vials promptly after each withdrawal to limit moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Lab Verification
Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Compounds are supplied as lyophilized research material — follow the storage and reconstitution guidance on the product page and its Certificate of Analysis.
Compound details.
- CAS Number
- 221231-10-3
- Molecular Weight
- 1815.08 g/mol
- Molecular Formula
- C₇₈H₁₂₃N₂₃O₂₃S₂
- Class
- Modified hGH Fragment
- Purity
- ≥99% purity
- Physical Form
- Lyophilized powder
- Storage
- Store at -20°C (long term). Refrigerate after reconstitution.
Research context.
Originally developed by Metabolic Pharmaceuticals and studied at Monash University, AOD9604 has been investigated in adipose tissue metabolism research. Published studies have explored its effects on lipogenesis inhibition and lipolysis stimulation in adipocyte models. It received GRAS (Generally Recognized as Safe) status from the FDA as a food ingredient in 2011.
Verification standard.
Independently verified Nexus Laboratory batches ship with a Certificate of Analysis documenting HPLC purity (target ≥98%), mass spectrometry identity (expected versus observed mass), and endotoxin context where applicable — verified by independent third-party laboratories and publicly archived; lots awaiting final documentation are labeled certificate pending instead of showing assay values. Review Nexus lab verification.
HPLC trace.
- HPLC purity
- 99.63%
- Retention time
- 13.5 min
- Batch
- NEX-AOD9604-2026-0008
The full reverse-phase HPLC chromatogram, peak integration table, and mass-spectrometry identity confirmation for this batch are published on the certificate of analysis.
View certificate of analysis - batch NEX-AOD9604-2026-0008- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
16-amino acid fragment of human growth hormone (hGH 176-191) with an N-terminal tyrosine
Storage: Store at -20°C (long term). Refrigerate after reconstitution.
Technical specifications.
- Product Name: AOD9604
- Classification: Modified hGH Fragment
- Structural Description: 16-amino acid fragment of human growth hormone (hGH 176-191) with an N-terminal tyrosine
- CAS Number: 221231-10-3
- Molecular Weight: 1815.08 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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AOD9604 research FAQ.
What is AOD9604 used for in research?
AOD9604 is supplied for controlled in-vitro research workflows in the Specialty Research category. It is not labeled for human or veterinary use.
Is AOD9604 HPLC verified?
AOD9604 has a finalized Nexus Lab Verified record with 99.63% HPLC purity context in the current COA data.
Which AOD9604 sizes are available?
Current Nexus variants include 2mg, 5mg, 10mg.
Does AOD9604 include a COA?
Yes. The current Nexus record links AOD9604 to verified batch NEX-AOD9604-2026-0008.