HGH Fragment 176-191

Compound Overview

HGH Fragment 176-191 represents the exact C-terminal 16 amino acids of human growth hormone. In contrast to AOD9604, which includes an additional N-terminal tyrosine, this compound is the unmodified native fragment. Laboratory research evaluates its isolated lipolytic signaling properties apart from the full-length hGH molecule.

Research Background & Published Literature

Monash University studies identified this region as the minimal active fragment associated with the fat metabolism effects of hGH. Published work has examined the isolated fragment in relation to lipogenesis and lipolysis without somatotropic activity.

Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:

• Wu et al. (1993) — Biochem Mol Biol Int
• Ng et al. (2000) — Horm Res
• Heffernan et al. (2001) — Endocrinology

Storage, Handling & Stability Guidelines

Store lyophilized HGH Fragment 176-191 at -20°C for long-term stability. After reconstitution with sterile diluent, keep research material refrigerated at 2–8°C and minimize freeze-thaw cycles by aliquoting working volumes according to your standard operating procedures.

• Keep ambient-temperature exposure brief during handling to help preserve compound integrity.
• Reseal vials promptly after each withdrawal to reduce moisture exposure.
• Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
• For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.

Lab Verification

Nexus maintains batch-level verification records for research compounds in the Lab Verified archive, including HPLC purity review and Mass Spectrometry identity confirmation where current lot data is available.