Epithalon
Epithalon from the Nexus Longevity & Cellular Health catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
Epithalon (Epitalon) is a synthetic tetrapeptide analog of epithalamin, a naturally occurring pineal gland peptide. Research investigates its ability to activate telomerase (hTERT), the enzyme responsible for maintaining telomere length. It is also studied for its effects on melatonin synthesis and circadian rhythm signaling.
No sequence is listed in the current catalog record for this product.
- CAS
- 307297-39-8
- MW
- 390.35 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C14H22N4O9
- Purity
- 99.73%
- Form
- Lyophilized powder
- Class
- Pineal Peptide / Telomerase Research Compound
The dossier.
Compound Overview
Epithalon (Epitalon) is a synthetic tetrapeptide analog of epithalamin, a naturally occurring pineal gland peptide. In controlled research models, investigators examine its role in telomerase (hTERT) activation, the enzyme system responsible for maintaining telomere length. It is also studied in relation to melatonin synthesis and circadian rhythm signaling.
Research Background & Published Literature
Prof. Vladimir Khavinson developed Epithalon at the Saint Petersburg Institute of Bioregulation and Gerontology. Published studies in Bulletin of Experimental Biology and Medicine and Neuroendocrinology Letters have evaluated telomerase activation and bioregulatory peptide signaling in laboratory research contexts.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
- Khavinson VKh et al. (2003) — Bull Exp Biol Med
- Khavinson VKh et al. (2004) — Bull Exp Biol Med
- Araj et al. (2025) — Int J Mol Sci
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep ambient-temperature handling time as short as practical to support compound integrity.
- Reseal vials promptly after each withdrawal to limit moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 307297-39-8
- Molecular Weight
- 390.35 g/mol
- Molecular Formula
- C₁₄H₂₂N₄O₉
- Class
- Pineal Peptide / Telomerase Research Compound
Research context.
Developed by Prof. Vladimir Khavinson at the Saint Petersburg Institute of Bioregulation and Gerontology. Published studies in Bulletin of Experimental Biology and Medicine and Neuroendocrinology Letters have examined its effects on telomerase activation and bioregulatory peptide signaling.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.73%
- Retention time
- 4.50 min
- Observed mass
- 390.42 Da
- Batch
- APX-2026-0311-E
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0311-E- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
The chemistry.
4-amino acid peptide (Ala-Glu-Asp-Gly), synthetic analog of epithalamin
Technical specifications.
- Product Name: Epithalon
- Classification: Pineal Peptide / Telomerase Research Compound
- Structural Description: 4-amino acid peptide (Ala-Glu-Asp-Gly), synthetic analog of epithalamin
- CAS Number: 307297-39-8
- Molecular Weight: 390.35 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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Research notes.
Epithalon research FAQ.
What is Epithalon used for in research?
Epithalon is supplied for controlled in-vitro research workflows in the Longevity & Cellular Health category. It is not labeled for human or veterinary use.
Does Epithalon have a finalized analytical record?
Epithalon has a finalized Nexus Lab Verified record that reports 99.73% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which Epithalon variants are published?
Published Nexus variants include 10mg, 40mg, 50mg.
Does Epithalon include a COA?
Yes. The current Nexus record links Epithalon to finalized batch APX-2026-0311-E.