Thymosin Alpha-1
Thymosin Alpha-1 from the Nexus Healing & Recovery catalog, supplied for controlled in-vitro research workflows.
Ships from the US with tracking.
Catalog active: Catalog pricing is active. Live warehouse counts are not published.
- Lot-specific COA
- HPLC + MS fields
- Batch archived
For in-vitro research use only. Not for human consumption.
Thymosin Alpha 1 (Tα1) is a 28-amino acid peptide originally isolated from thymic tissue. It activates toll-like receptors (TLR2, TLR9), enhances dendritic cell maturation, and stimulates T-cell differentiation. Research examines its role in innate and adaptive immune signaling.
No sequence is listed in the current catalog record for this product.
- CAS
- 62304-98-7
- MW
- 3108.28 g/mol
- Sequence
- Not listed
- Half-life
- Not listed
- Formula
- C129H215N33O55
- Purity
- 99.53%
- Form
- Lyophilized powder
- Class
- Immunomodulatory Peptide / Thymic Peptide
The dossier.
Compound Overview
Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide originally isolated from thymic tissue. In laboratory research, it is described as activating toll-like receptors (TLR2, TLR9), enhancing dendritic cell maturation, and stimulating T-cell differentiation. Controlled studies examine its role in innate and adaptive immune signaling.
Research Background & Published Literature
The same molecule is marketed as Zadaxin in over 30 countries; Nexus supplies this material only as a research reagent, not as a drug product. Published literature includes hundreds of studies spanning hepatitis, immunodeficiency, and vaccine adjuvant research, with work appearing in Journal of Biological Chemistry and Clinical Infectious Diseases.
Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications:
- Wu et al. (2013) — Crit Care
- Wang et al. (2011) — Inflammation
- Mandaliti et al. (2018) — Expert Opin Biol Ther
Storage, Handling & Stability Guidelines
Use the applicable lot/source record for storage of unopened material. Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP; this page does not establish a stability window.
- Keep ambient-temperature handling time as short as practical to support compound integrity.
- Reseal vials promptly after each withdrawal to reduce moisture exposure.
- Use appropriate personal protective equipment and follow institutional chemical safety protocols at all times.
- For traceability, label all aliquots with compound name, concentration, reconstitution date, and operator initials.
Quality Assurance & Lab Verification
A finalized public Certificate of Analysis is available for this catalog item. Review the public COA for the applicable lot. Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier.
Shipping
Orders ship within the United States via USPS; international orders are not accepted. Laboratories should follow their validated SOP together with any handling fields published for the represented product or lot; no universal prepared-solution condition is inferred here.
Compound details.
- CAS Number
- 62304-98-7
- Molecular Weight
- 3108.28 g/mol
- Molecular Formula
- C₁₂₉H₂₁₅N₃₃O₅₅
- Class
- Immunomodulatory Peptide / Thymic Peptide
Research context.
Marketed as Zadaxin in over 30 countries. Published in hundreds of studies spanning hepatitis, immunodeficiency, and vaccine adjuvant research. Studied in Journal of Biological Chemistry and Clinical Infectious Diseases.
Verification standard.
Certificate information is lot-specific. A finalized public record shows only the methods, fields, and results present for that named lot. A pending certificate state exposes no assay values and must not be interpreted as analytical verification. Review Nexus lab verification.
Analytical record.
- Reported HPLC purity
- 99.53%
- Retention time
- 14.50 min
- Observed mass
- 3108.52 Da
- Batch
- APX-2026-0415-T
The normalized Certificate of Analysis publishes only the lot-specific fields represented in the public record. It is not an originating laboratory report or raw instrument file.
View certificate of analysis - batch APX-2026-0415-T- Sequence
- Not listed
- Model preview
- Unavailable
Molecular model preview is unavailable for this catalog record.
Technical specifications.
- Product Name: Thymosin Alpha 1
- Classification: Immunomodulatory Peptide / Thymic Peptide
- Structural Description: 28-amino acid peptide derived from prothymosin alpha
- CAS Number: 62304-98-7
- Molecular Weight: 3108.28 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
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Thymosin Alpha-1 research FAQ.
What is Thymosin Alpha-1 used for in research?
Thymosin Alpha-1 is supplied for controlled in-vitro research workflows in the Healing & Recovery category. It is not labeled for human or veterinary use.
Does Thymosin Alpha-1 have a finalized analytical record?
Thymosin Alpha-1 has a finalized Nexus Lab Verified record that reports 99.53% HPLC area-percent purity for the represented batch. Other fields are shown only where present.
Which Thymosin Alpha-1 variants are published?
Published Nexus variants include 2mg, 5mg, 10mg.
Does Thymosin Alpha-1 include a COA?
Yes. The current Nexus record links Thymosin Alpha-1 to finalized batch APX-2026-0415-T.